Publications

Visit Dr. Otto’s Google Scholar page

2025

• B Biney, QW Dong, CC Eluagu, K Otto, ME Orazem. Understanding the Electrode-Tissue Interface in Neural Stimulation through Impedance Spectroscopy. AIChE Annual Meeting. [Link]
• H Lutz, Y Wu, CC Eluagu, S Cogan, KJ Otto, ME Orazem. Electrochemical Impedance Spectroscopy of Sputtered Iridium Oxide Electrodes for Neural Applications. 248th ECS Meeting. [Link]
• L Dewberry, C Cruz, K Southern, K Otto, K Allen. Pipeline Validation for Rodent Gait Analysis Using DeepLabCut. Journal of Biomechanical Engineering. [Link]
• Bernard W Biney, Sophia Carvalho, Henry Lutz, Cynthia C Eluagu, Elizabeth Marie Olivo, QiWei Dong, Stuart Cogan, Kevin John Otto, Mark E Orazem. Electrochemical Impedance Spectroscopy for Implanted Electrodes. Electrochemical Society Meeting Abstracts. [Link]
• Kelsey Ariel Sinclair, Cynthia C. Eluagu, Bernard W. Biney, Elizabeth Marie Olivo, QiWei Dong, Yupeng Wu, Stuart Cogan, Kevin John Otto and Mark E. Orazem. Interpretation of Impedance Spectra for Neural Stimulation Devices. Electrochemical Society Meeting Abstracts. [Link]
• Henry M Lutz, Yupeng Wu, Cynthia C Eluagu, Stuart F Cogan, Kevin J Otto, Mark E Orazem. Analysis of electrochemical impedance spectroscopy data for sputtered iridium oxide electrodes. Journal of Neural Engineering 2025.[Link]

2024

• Qiwei Dong, Cynthia Ezeh, Yupeng Wu, Jamille F Hetke, Stuart Cogan, Mark E Orazem, Kevin J Otto. Stability Assessment of Ultramicroelectrode Arrays in Neural Stimulation: an Electrochemical Impedance Spectroscopy Analysis. IEEE Conference Engineering in Medicine and Biology Society (EMBC) 2024. [Link]
• Cassandra Acebal, Gurleen Kainth, Harry Villanueva, Ava Hajjar, Valery Fuhrer, Paul Wanczuk, Alexander S Lim, Shriya Srinivasan, Kevin J Otto, Adam Khalifa. A Method for Minimally-Invasive Injection of Wireless Microdevices into Brain Tissue. IEEE Conference Engineering in Medicine and Biology Society (EMBC) 2024. [Link]
• Yupeng Wu, Miguel Figueroa Hernández, Tian Lei, Siddarth Jayakumar, Rohan R Lalapet, Alexandra Joshi-Imre, Mark E Orazem, Kevin J Otto, Stuart F Co. The Effect of Physical Structural Properties on Electrochemical Properties of Ruthenium Oxide for Neural Stimulating and Recording Electrodes.  IEEE Conference Engineering in Medicine and Biology Society (EMBC) 2024. [Link]
• KP O’Sullivan, ME Orazem, KJ Otto, CR Butson, JL Baker. Electrical rejuvenation of chronically implanted macroelectrodes in nonhuman primates. Journal of Neural Engineering 2024. [Link]
• Kyle P O’Sullivan, Brian J Philip, Jonathan L Baker, John D Rolston, Mark E Orazem, Kevin J Otto, Christopher R Butson. In Vivo and In Vitro Electrochemical Impedance Spectroscopy of Acute and Chronic Intracranial Electrodes. Data 2024.[Link]
• Kundu A, E Patrick, S Currlin, R Madler, F Delgado, A Fahmy, R Verplancke, M Ballini, D Braeken, M Op de Beeck, N Maghari, K Otto, R Bashirullah. Using compound neural action potentials for functional validation of a high-density intraneural interface: a preliminary study. Micromachines 2024. [Link]

2023

• Dirr E, L Jiracek, D Baekey, C Martyniuk, K Otto, J Zubcevic. Subdiaphragmatic vagal nerve stimulation attenuates the progression of hypertension and alters NTS transcriptional networks in the SHR. Physiological Genomics 2023. [Link]
• Dewberry LS, K Porche, T Koenig, KD Allen, KJ Otto. High Frequency Alternating Current Neurostimulation Decreases Nocifensive Behavior in a Disc Herniation Model of Lumbar Radiculopathy. Bioelectronic Medicine 2023. [Link]
• Dirr E, Y Patel, RD Johnson, KJ Otto. The effects of targeted vagus nerve stimulation on glucose homeostasis in STZ-induced diabetic rodents. Frontiers in Neuroscience – Autonomic Neuroscience 2023. [Link]
• O’Sullivan KP, JL Baker, B Philip, ME Orazem, KJ Otto, CR Butson. In vivo application of electrical rejuvenation pulses to chronically implanted neural macroelectrodes in nonhuman primates for regulation of interface properties. IEEE Neural Engineering Conference 2023. [Link]
• Urdaneta ME, NG Kunigk, JD Penaloza-Aponte, S Currlin, IG Malone, SI Fried, KJ Otto. Layer-dependent stability of intracortical recordings and neuronal cell loss. Frontiers in Neuroscience – Neuroprosthetics 2023. [Link]
• ME Orazem, KJ Otto, CL Alexander. Electrochemistry in Action-Engineering the Neuronal Response to Electrical Microstimulation. The Electrochemical Society Interface 2023. [Link]
• Cruz, CJ, L Dewberry, KJ Otto, and KD Allen. Neuromodulation as a Potential Disease-Modifying Therapy for Osteoarthritis. Current Rheumatology Reports 2023. [Link]

2022

• Atkinson E, CA Kuliasha, M Kasper M, AS Lim, LG Jiracek-Sapieha, AM Brake, A Gormaley, VG Rivera-Llabres, I Singh, BS Spearman, CM Rinaldi-Ramos, CE Schmidt, JW Judy, and KJ Otto. Examining the in vivo Functionality of the Magnetically Aligned Regenerative Tissue-Engineered Electronic Nerve Interface (MARTEENI). Journal of Neural Engineering 2022. [Link]
• Kunigk NG, Urdaneta ME, Malone IG, Delgado F, KJ Otto. Reducing Behavioral Detection Thresholds per Electrode via Synchronous, Spatially-Dependent Intracortical Microstimulation. Frontiers in Neuroscience 2022. [Link]
• Urdaneta ME, NG Kunigk, S Currlin, F Delgado, SI Fried, KJ Otto. The long-term stability of intracortical microstimulation and the foreign body response are layer dependent. Frontiers in Neuroscience 2022. [Link]
• Malone IG, MN Kelly, RL Nosacka, MA Nash, S Yue, W Xue, KJ Otto, and EA Dale. Closed-Loop, Cervical, Epidural Stimulation Elicits Respiratory Neuroplasticity after Spinal Cord Injury in Freely Behaving Rats. eNeuro 2022. [Link]

2021

• Kasper M, B Ellenbogen, R Hardy, M Cydis, J Mojica-Santiago, A Afridi, BS Spearman, I Singh, CA Kuliasha, E Atkinson, KJ Otto, JW Judy, C Rinaldi, CE Schmidt. Development of a magnetically aligned regenerative tissue-engineered electronic nerve interface for peripheral nerve applications. Biomaterials 2021. [Link] 
• Saldanha, RL, ME Urdaneta, KJ Otto. The role of electrode-site placement in the long-term stability of intracortical microstimulation. Frontiers in Neuroscience 2021. [Link]
• Olczak K, KJ Otto. The role of ascorbic acid oxidation during neural stimulation. Journal of The Electrochemical Society 2021. [Link]
• Altidor, LK-P, MM Bruner, JF Deslauriers, TS Garman, SRamirez, DG Lamb, EW Dirr, KP Olczak, AP Maurer, KJ Otto, SN Burke, AV Bumanglag, B Setlow, JL Bizon. Acute vagus nerve stimulation enhances reversal learning in rats. Neurobiology of Learning and Memory 2021. [Link]
• Malone I, R Nosacka, KJ Otto, E Dale. Electrical epidural stimulation: Implications for spinal respiratory plasticity after spinal cord injury. Journal of Neurophysiology 2021. [Link]
• Abuid, NJ, ME Urdaneta, KM Gattas-Asfura, C Zientek, CI Silgo, JA Torres, KJ Otto, CL Stabler. Engineering the multienzymatic activity of cerium oxide nanoparticle coatings for the antioxidant protection of implants. Advanced NanoBiomed Research 2021. [Link]
• Vedam-Mai, V., Deisseroth, K., Giordano, J., Lazaro-Munoz, G., Chiong, W., Suthana, N., Langevin, J.-P., Gill, J., Goodman, W., Provenza, N. R., Halpern, C. H., Shivacharan, R. S., Cunningham, T. N., Sheth, S. A., Pouratian, N., Scangos, K. W., Mayberg, H. S., Horn, A., Johnson, K. A., … Okun, M. S. (2021). Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Frontiers in Human Neuroscience 2021. [Link]
• Urdaneta ME, NG Kunigk, F Delgado, SI Fried, KJ Otto. Layer-specific parameters of intracortical microstimulation of the somatosensory cortex. Journal of Neural Engineering 2021. [Link]
• Kundu A, A Fahmy, R Madler, K Otto, E Patrick, J Principe, N Maghari, R Bashirullah. A Multi-Channel Peripheral Nerve Stimulator with Integrate-and-Fire Encoding. Journal of Medical Engineering & Technology 2021. [Link]
• Sunshine MD, AM Cassarà, E Neufeld, N Grossman, TH Mareci, KJ Otto, ES Boyden, DD Fuller. Restoration of breathing after opioid overdose and spinal cord injury using temporal interference stimulation. Communications Biology 2021. [Link]
• Dewberry LS, A Dru, M Gravenstine, B Nguyen, J Anderson, S Vaziri, D Hoh, K Allen, KJ Otto. Partial high frequency nerve block decreases neuropathic signaling following chronic sciatic nerve constriction injury. Journal of Neural Engineering 2021. [Link]

2020

• Olczak KP and KJ Otto. Coatings for Microneural Implants: Electrical Considerations. In N. v Thakor (Ed.), Handbook of Neuroengineering (pp. 1–34). Springer Singapore 2020. [Link]
• Olczak KP and KJ Otto. Coatings for Microneural Implants: Biological and Mechanical Considerations. In N. v Thakor (Ed.), Handbook of Neuroengineering (pp. 1–38). Springer, Singapore 2020. [Link]
• Lester LE, E Dirr, KJ Otto. Design of Pulse Oximeter Solution for Conscious Rodents. UF Journal of Undergraduate Research 2020. [Link]
• Dirr EW, ME Urdaneta, Y Patel, RD Johnson, M Campbell-Thompson, KJ Otto. Designing a bioelectronic treatment for Type 1 diabetes: targeted parasympathetic modulation of insulin secretion. Future Medicine 2020. [Link]
• Esquibel CR, KD Wendt, HC Lee, J Gaire, A Shoffstall, ME Urdaneta, JV Chacko, SK Brodnick, KJ Otto Kevin, JR Capadona, JC Williams, KW Eliceiri. Second Harmonic Generation Imaging of Collagen in Chronically Implantable Electrodes in Brain Tissue. Frontiers in Neuroscience 2020. [Link]
• Otto KJ, CE Schmidt. Neuron-targeted electrical modulation. Science 2020. [Link]

2019

• Verplancke R, M Cauwe, D Schaubroeck, D Cuypers, B Vandecasteele, L Mader, C Vanhaverbeke, M Ballini, J O’Callaghan, E Goikoetxea, D Braeken, A Kundu, E Patrick, N Maghari, KJ Otto, R Bashirullah, M Op de Beeck. Development of an active high-density transverse intrafascicular micro-electrode (hd-TIME) probe. Journal of Micromechanics and Microengineering 2019. [Link]
• Olczak, KP, M McDermott, KJ Otto. Electrochemical Evaluation of Layer-by-Layer Drug Delivery Coating for Neural Interfaces. ACS Applied Bio Materials 2019. [Link]
• HuBMAP Consortium. The human body at cellular resolution: the NIH Human Biomolecular Atlas Program. Nature 2019. [Link]
• Ereifej, ES, CE Shell, JS Schofield, H Charkhkar, I Cuberovic, AD Dorval, EL Graczyk, TDY Kozai, KJ Otto, DJ Tyler, CG Welle, AS Widge, J Zariffa, CT Moritz, DJ Bourbeau, PD Marasco. Neural engineering: the process, applications, and its role in the future of medicine. Journal of Neural Engineering 2019. [Link]
• Tyler DJ, CJ Czura, J French, K Ludwig, K Otto, F Pape, and C Welle. Cleveland neural engineering workshop 2017: strategic evaluation of neural engineering. Bioelectronic Medicine 2019. [Link]

2018

• Gaire, J, HC Lee, N Hilborn, R Ward, M Regan, KJ Otto. The role of inflammation on the functionality of intracortical microelectrodes. Journal of Neural Engineering 2018. [Link]
• Murbach JM, S Currlin, A Widener, Y Tong, S Chhatre, V Subramanian, DC Martin, BN Johnson, and KJ Otto. In situ electrochemical polymerization of poly(3,4-ethylenedioxythiophene) (PEDOT) for peripheral nerve interfaces. MRS Communications 2018. [Link|]
• Gaire, J, HC Lee, R Ward, S Currlin, AJ Woolley, JE Coleman, JC Williams, KJ Otto. PrismPlus: a mouse line expressing distinct fluorophores in four different brain cell types. Scientific Reports 2018. [Link|PDF]
• Butterworth, E, W Dickerson, V Vijay, K Weitzel, J Cooper, E Atkinson, J Coleman, KJ Otto, M Campbell-Thompson. High Resolution 3D Imaging of the Human Pancreas Neuro-insular Network Jove 2018. [Video]
• Park, D, J Ness, S Brodnick, C Esquibel, J Novello, F Atry, D Baek, H Kim, J Bong, K Swanson, A Suminski, KJ Otto, R Pashaie, J Williams, Z Ma. Electrical Neural Stimulation and Simultaneous in Vivo Monitoring with Transparent Graphene Electrode Arrays Implanted in GCaMP6f Mice. ACS NANO 2018. [PDF]
• Lee, HC, J Gaire, B Roysam, KJ Otto. Placing sites on the edge of a planar silicon microelectrode enhances chronic recording functionality. IEEE Transactions on Biomedical Engineering 2018.[PDF]

2017

• Urdaneta, M, AS Koivuniemi, KJ Otto. Central nervous system microstimulation: Towards selective micro-neuromodulation. Current Opinion in Biomedical Engineering. 2017. [PDF]
• Lee, HC, J Gaire, S Currlin, M McDermott, K Park, KJ Otto. Foreign Body Response to Intracortical Microelectrodes Is Not Altered with Dip-Coating of Polyethylene Glycol (PEG). Frontiers in Neuroscience. 2017. [PDF]
• Spearman, B, V Desai, S Mobini, M Mc.Dermott, J Graham, KJ Otto, J Judy, C Schmidt. Tissue-Engineered Peripheral Nerve Interfaces. Advanced Functional Materials. 2017. [PDF]
• Nunamaker, E, B Spearman, J Graham, E Atkinson, V Desai, C Shafor, S Natt, R Wachs, C Schmidt, J Judy, K Otto. Implantation methodology development for tissue-engineered-electronic-neural-interface (TEENI) devices. IEEE EMBS Conference. 2017. [PDF]
• Desai, V, B Spearman, C Shafor, S Natt, B Teem, J Graham, E Atkinson, R Wachs, E Nunamaker, KJ Otto, C Schmidt, J Judy. Design, fabrication, and characterization of a scalable tissue-engineered-electronic-nerve-interface (TEENI) device. IEEE EMBS Conference. 2017. [PDF]
• Graham, J, E Atkinson, E Nunamaker, B Spearman, V Desai, C Shafor, S Natt, R Wachs, C Schmidt, J Judy, KJ Otto. Histological evluation of chronically implanted tissue-engineered-electronic-neural-interface (TEENI) devices. IEEE EMBS Conference. 2017. [PDF]
• Lee, HC, F Ejserholm, J Gaire, S Currlin, J Schouenborg, L Wallman, M Bengtsson, K Park, KJ Otto. Histological evaluation of flexible neural implants; flexibility limit for reducing the tissue response? Journal of Neural Engineering. 14(3). 2017.[ PDF]
• McDermott, M, KP Olczak, KJ Otto. Electrical Analysis of Minocycline Eluting Layer-By-Layer Thin-Films from Functional Micro-Electrode Arrays 8th International IEEE EMBS Conference on Neural Engineering. 2017. [PDF]

2016

• McDermott, M, KJ Otto. The effect of multiple thin-film coatings of protein loaded sol-gel on total multi-electrode array thickness. 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). pp. 129-132. 2016. [PDF]
• Rossi, PJ, A Gunduz, J Judy, et al. The Third Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies. Frontiers in Neuroprosthetics. 2016. [PDF]

2015

• Rajan, AT, JL Boback, JF Dammann, FV Tenore, BA Wester, KJ Otto, RA Gaunt, SJ Bensmaia. The effects of chronic intracortical microstimulation on neural tissue and fine motor behavior. Journal of Neural Engineering. 12 (6), 066018. 2015. [PDF]
• Vedam-Mai, V, AT Yachnis, KJ Otto, A Gunduz, AW Shukla, C Hess, MS Okun. Histopathological observations from 50 human deep brain stimulation cases. Movement Disorders. Vol. 30. pp. S292. 2015.
• McDermott MD, J Zhang, KJ Otto. Improving the brain machine interface via multiple Tetramethyl Orthosilicate sol-gel coatings on microelectrode arrays. Proceedings of the 7th International IEEE/EMBS Conference on Neural Engineering. 2015. [PDF]
• Ward, M, K Otto, K Qing, R Worth, S John, and P Irazoqui. A flexible platform for biofeedback-driven control and personalization of electrical nerve stimulation therapy. IEEE Transactions on Neural Systems and Rehabilitation Engineering PP(99):1-1. 2015. [PDF]
• Wodicka, JR, NI Onunkwo, AJ Woolley, A Panitch, and KJ Otto. A cell-penetrating peptide for inhibiting MAPKAP Kinase 2-mediated inflammatory cytokine release following glial cell activation. World Journal of Neuroscience 5 (02), 115. 2015. [PDF]

2014

• Sommakia, S, JL Rickus, and KJ Otto. Glial cells, but not neurons, exhibit a controllable response to a localized inflammatory microenvironment in vitro. Frontiers in Neuroengineering. 14;7:41. doi: 10.3389/fneng.2014.00041. 2014. [PDF]
• Koivuniemi, AS and KJ Otto. When “Altering Brain Function” becomes “Mind Control”. Frontiers in Systems Neuroscience. 14;8:202. doi: 10.3389/fnsys.2014.00202. 2014. [PDF]
• Sommakia, S, HC Lee, J Gaire, and KJ Otto. Materials approaches for modulating neural tissue responses to implanted microelectrodes through mechanical and biochemical means. Current Opinion in Solid State & Materials Science. 18 (6), 319-328, 2014. [PDF]
• Lycke, R, A Schendel, JC Williams, and KJ Otto. In vivo evaluation of a μECoG array for chronic stimulation. Proceedings of the 36th Annual IEEE EMBS International Conference, 2014. [PDF]
• Lee, HC, J Gaire, S McDowell, and KJ Otto. The effect of site placement within silicon microelectrodes on the long-term electrophysiological recordings. Proceedings of the 36th Annual IEEE EMBS International Conference, 2014. [PDF]
• Sommakia, S, S Wyatt, KJ Otto, A Vadlamani, AL Garner. Nanosecond pulsed electric field interactions with microglia and astrocytes. 2014 IEEE International Power Modulator and High Voltage Conference, doi: 10.1109/IPMHVC.2014.7287296, 2014. [PDF]
• Sommakia, S, J Gaire, JL Rickus, KJ Otto. Resistive and reactive changes to the impedance of intracortical microelectrodes can be mitigated with polyethylene glycol under acute in vitro and in vivo settings. Frontiers in Neuroengineering, doi: 10.3389/fneng.2014.00033, 2014. [PDF]
• Ward, M, K Otto, K Qing, R Worth, S John, and P Irazoqui. A flexible platform for biofeedback-driven control and personalization of electrical nerve stimulation therapy. IEEE Transactions on Neural Systems and Rehabilitation Engineering, PP(99):1-1. 2014. [PDF]
• Chen KH, JF Dammann, JL Boback, FV Tenore, KJ Otto, RA Gaunt, and SJ Bensmaia. The effect of chronic intracortical microstimulation on the electrode-tissue interface. Journal of Neural Engineering. 11 026004. doi:10.1088/1741-2560/11/2/026004. 2014. [PDF]

2013

• Woolley, AJ, HA Desai, J Gaire, AL Ready, and KJ Otto. A systemic triple label strategy for fluorescent microscopy of inflammation in CNS and non-CNS tissue. Microscopy and Microanalysis. 19(S2):196-197. 2013. [PDF]
• Regele, OB, AS Koivuniemi, KJ Otto. Constant RMS versus constant peak modulation for the perceptual equivalence of sinusoidal amplitude modulated signals. Proceedings of the 35th Annual IEEE EMBS International Conference. 3115-3118. 2013. [PDF]
• Woolley, AJ, HA Desai, and KJ Otto. Chronic intracortical microelectrode arrays induce non-uniform, depth-related tissue responses. Journal of Neural Engineering. 10(2):026007. 2013. [PDF]
• Ochoa, M, P Wei, AJ Woolley, KJ Otto, and B Ziaie. A hybrid PDMS-Parylene subdural multi-electrode array. Biomedical Microdevices, DOI 10.1007/s10544-013-9743-2. 2013. [PDF]
• Woolley, AJ, HA Desai, J Gaire, AL Ready, and KJ Otto. Intact histological characterization of brain-implanted microdevices and surrounding tissue. Journal of Visualized Experiments, (72), e50126, doi:10.3791/50126. 2013. [Video]
• Nunamaker, EA, KJ Otto, JE Artwohl, and JD Fortman. Leaching of heavy metals from water bottle components into the drinking water of rodents. Journal of the American Association for Laboratory Animal Science, 52(1):22-27. 2013. [PDF]

2012

• Sundararajan, R, F Xiao, T Salameh, LM Reece, L Campana, IG Camarillo, JF Leary, and KJ Otto. Effective proliferation control of human cancer cells using electrical pulses. IEEE Transactions on Dielectrics and Electrical Insulation. 19(6):2225-2236. 2012. [PDF]
• Koivuniemi, AS and KJ Otto. The depth, waveform, and pulse rate for electrical microstimulation of the auditory cortex. Proceedings of the 34th Annual IEEE EMBS International Conference, 2489-92. 2012. [PDF]
• Sundararajan, R, F Xiao, KJ Otto, and IG Camarillo. The dielectric properties of electroporated human breast cancer cells. 2012 IEEE 10th International Conference on the Properties and Applications of Dielectric Materials (ICPADM). 2012.[PDF]
• Otto, KJ and JC Williams. Novel In Vitro and In Vivo Neural Interfaces. IEEE Pulse. 2012. [PDF]
• Wilks, SJ, TJ Richner, JC Williams, and KJ Otto. Voltage Biasing, Cyclic Voltammetry, & Electrical Impedance Spectroscopy for Neural Interfaces. Journal of Visualized Experiments. 2012. [Video]

2011

• Koivuniemi, AS, OB Regele, JH Brenner, and KJ Otto. Rat Behavioral Model for High-Throughput Parametric Studies of Intracortical Microstimulation. Proceedings of the 33rd Annual IEEE EMBC International Conference. 2011. [PDF]
• Wilks, SJ, AJ Woolley, L Ouyang, DC Martin, and KJ Otto. In Vivo Polymerization of Poly(3,4-ethylenedioxythiophene) (PEDOT) in Rodent Cerebral Cortex. Proceedings of the 33rd Annual IEEE EMBC International Conference. 2011. [PDF]
• Koivuniemi, AS, and KJ Otto. Asymmetric Versus Symmetric Pulses for Cortical Microstimulation. IEEE Transactions in Neural Systems and Rehabilitation, 19(5):468-476. 2011. [PDF]
• Koivuniemi, AS, SJ Wilks, AJ Woolley, and KJ Otto. Multimodal, longitudinal assessment of intracortical microstimulation. Progress in Brain Research, 194:131-144. 2011. [PDF]
• Lempka, S, MD Johnson, M Moffitt, KJ Otto, DR Kipke, and C McIntyre. Theoretical Analysis of Intracortical Microelectrode Recordings. Journal of Neural Engineering, 8 045006. 2011. [PDF]
• Woolley, AJ, H Desai, MA Steckbeck, N Patel, and KJ Otto. In situ characterization of the brain-microdevice interface using Device Capture Histology. Journal of Neuroscience Methods 201:67-77. 2011. [PDF]
• McCarthy, PT, MP Rao, and KJ Otto. Simultaneous recording of rat auditory cortex and thalamus via a titanium-based multi-channel, microelectrode device. Journal of Neural Engineering, 8 046007. 2011. [PDF]
• McCarthy, PT, KJ Otto, and MP Rao. Robust penetrating microelectrodes for neural interfaces realized by titanium micromachining. Biomedical Microdevices, DOI 10.1007/s10544-011-9519-5. 2011. [PDF]

2010

• Nunamaker, EA, KJ Otto, and DR Kipke. Investigation of the material properties of alginate for the development of hydrogel repair of dura mater. Journal of the Mechanical Behavior of Biomedical Materials, 4(1):16-33. 2010. [PDF]

2009

• Xiao, F, KJ Otto, I Camarillo, R Sundararajan. Impedance spectroscopy studies of electroporated human breast cancer cells. Proceedings of the CEIDP ’09. IEEE Conference on Electrical Insulation and Dielectric Phenomena, 470-3. 2009. [PDF]
• McCarthy, PT, R Madangopal, KJ Otto, and MP Rao. Titanium-based multi-channel, micro-electrode array for recording neural signals. Proceedings of the 31st Annual IEEE EMBC International Conference, 2062-5. 2009. [PDF]
• Sommakia, SS, Rickus, JL, and KJ Otto. Effects of adsorbed proteins and an antifouling agent and long-duration DC voltage pulses on the impedance of silicon-based neural microelectrodes. Proceedings of the 31st Annual IEEE EMBC International Conference, 7139-42. 2009. [PDF]
• Wilks, SJ, AS Koivuniemi, S Thongpang, JC Williams, and KJ Otto. Evaluation of micro-electrocorticographic electrodes for electrostimulation. Proceedings of the 31st Annual IEEE EMBC International Conference, 5510-3. 2009. [PDF]
• Wilks, SJ, SM Richardson-Burns, JL Hendricks, DC Martin, and KJ Otto. Poly(3,4-ethylene dioxythiophene) (PEDOT) as a micro-neural interface material for electrostimulation. Frontiers in Neuroengineering, 2:7. Doi:10.3389/neuro.16.007.2009. 2009. [PDF]
• Pierce, AL, S Sommakia, RL Rickus, and KJ Otto. Thin Film Silica Sol-Gel Coatings for Neural Microelectrodes. Journal of Neuroscience Methods, 180:106-110. 2009. [PDF]

2008

• Elman A, E Bartlett, N Kong, and KJ Otto. Analysis of Sensory Transformations in Response to Complex Sensory Stimuli in the Auditory Pathway. Proceedings of the 3rd INFORMS Workshop on Data Mining and Health Informatics, DM-HI. 2008. [PDF]
• Sundararajan, R, D Campbell, J Harper, F Xiao, R Ma, and KJ Otto. Characterization of fruit juices treated with electrical pulses. Annual Report of the IEEE Conference on Electrical Insulation & Dielectric Phenomena. 26-29 Oct., 1:536-539. 2008. [PDF]

2006

• Otto, KJ, MD Johnson, and DR Kipke. Voltage Pulses Change Neural Interface Properties and Improve Unit Recordings with Chronically Implanted Microelectrodes. IEEE Transactions on Biomedical Engineering, 53(2):333-40. 2006. [PDF]
• Lempka, SF, MD Johnson, DW Barnett, MA Moffitt, KJ Otto, DR Kipke and CC McIntyre. Optimization of microelectrode design for cortical recording based on thermal noise considerations. Proceedings of the 28th Annual IEEE EMBC International Conference, 1:3361-3364. 2006. [PDF]

2005

• Otto, KJ, PJ Rousche, and DR Kipke. Microstimulation in Auditory Cortex Provides a Substrate for Detailed Behaviors. Hearing Research, 210(1-2):112-117. 2005. [PDF]
• Otto, KJ, PJ Rousche, and DR Kipke. Cortical microstimulation in auditory cortex of rat elicits best-frequency dependent behaviors. Journal of Neural Engineering, 2:42-51. 2005. [PDF]
• Johnson, MD, KJ Otto, and DR Kipke. Repeated voltage biasing improves unit recordings by reducing resistive tissue impedances, (Invited). IEEE Transactions on Neural Systems and Rehabilitation Engineering, 13(2):160-165. 2005. [PDF]
• Gage, GJ, KA Ludwig, KJ Otto, EL Ionides, DR Kipke. Naïve coadaptive cortical control. Journal of Neural Engineering, 2:52-63. 2005. [PDF]

2004

• Johnson MD, KJ Otto, JC Williams, and DR Kipke. Bias voltages at microelectrodes change neural interface properties in vivo. Proceedings of the 26th Annual IEEE EMBS International Conference. 6:4103-4106. 2004. [PDF]
• Ghovanloo M, KJ Otto, DR Kipke, and K Najafi. In vitro and in vivo testing of a wireless multichannel stimulating telemetry microsystem. Proceedings of the 26th Annual IEEE EMBS International Conference. 6:4294-4297. 2004. [PDF]
• Gage GJ, KJ Otto, KA Ludwig, and DR Kipke. Co-adaptive Kalman filtering in a naive rat cortical control task. Proceedings of the 26th Annual IEEE EMBS International Conference. 6:4367-4370. 2004. [PDF]

2003

• Otto, KJ, PJ Rousche, and DR Kipke. The benefits of modular brain-machine interface system design. Proceedings of the 25th Annual IEEE EMBS International Conference. 3: 2208-2211. 2003. [PDF]
• Otto, KJ, RJ Vetter, TC Marzullo, and DR Kipke. Brain-machine interfaces in rat motor cortex: implication of adaptive decoding algorithms. Proceedings of the 1st International IEEE EMBS Conference on Neural Engineering. 1:100-103. 2003. [PDF]
• Vetter, RJ, KJ Otto, TC Marzullo, and DR Kipke. Brain-machine interfaces in rat motor cortex: neuronal operant conditioning to perform a sensory detection task. Proceedings of the 1st International IEEE EMBS Conference on Neural Engineering. 1:637-640. 2003. [PDF]
• Rousche, PJ, KJ Otto, and DR Kipke. Single electrode micro-stimulation of rat auditory cortex: an evaluation of behavioral performance. Hearing Research, 179(1-2): p. 62-71. 2003. [PDF]
• Otto, KJ. Intracortical microstimulation for sensory inputs in brain-machine interfaces. Ph.D. Dissertation, Arizona State University, Tempe, AZ. [PDF]

1999

• Witte, RS, KJ Otto, JC Williams, and DR Kipke. Pursuing dynamic reorganization in auditory cortex using chronic multichannel unit recordings in awake, behaving cats. Neurocomputing, 26-27:593-600. 1999. [PDF]